The Single Best Strategy To Use For ceesdekker

The Single Best Strategy To Use For ceesdekker

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‘The second is nanopores, which is our oldest line of study and which has now triggered DNA sequencers based on nanopores. We pull person DNA strands through a nanopore and will then browse from the nucleotide sequence. Incredibly a short while ago, we even managed to examine out one protein for The very first time utilizing this technique. But this line of research is don't just about producing instruments, but in addition about genuine Organic issues.

Human Rad51 filaments on double- and solitary-stranded DNA: correlating regular and irregular kinds with recombination functionality.

Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initially ever analyze in the dynamics DNA supercoils and the invention of supercoil hopping

The coiled-coil from the human Rad50 DNA repair protein has certain segments of improved flexibility

Duration Charge of specific carbon nanotubes by nanostructuring Along with the scanning tunneling microscope

Finding out DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.

2003, shown the primary biosensors manufactured from a carbon nanotube; resolved the composition and system of DNA fix proteins; and discovery of a fresh method for fabricating solid-point out nanopores ceesdekker for DNA translocation

Dekker started off his analysis on single carbon nanotubes in 1993 when he build a fresh line of research to check electrical transport as a result of solitary organic molecules involving nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was obtained within a collaboration with the team of Nobel laureate Richard Smalley. STM and nanolithography methods ended up accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with fantastic physical Homes.

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Cees Dekker is Distinguished University Professor at TU Delft. Educated as a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes within the 1990s. Since 2000, he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, specifically SMC motor protein; and (iii) creating a living artificial mobile from lifeless molecules. Dekker is undoubtedly an elected member on the KNAW and fellow for the APS as well as the IOP.

Developments in nanotechnology within the 1990s produced creating electronic gadgets from single molecules a possibility. Cees Dekker recounts how his team produced a room-temperature transistor based on a single carbon nanotube.

The biophysicist from Delft – who has long been One of the more cited researchers inside the Netherlands For many years – requires his obligation to lead for the explanation and popularisation of his do the job for the border of physics and biology really critically and frequently seems inside the media; if not to look at his operate, then about the relationship involving science and his Christian faith.